Russian Scientists Develop ‘Perfect’ Molecules for Pharmacology
Researchers from Ural Federal University (UrFU), in collaboration with a scientific team, have developed and experimentally tested a new method for producing synthetic analogs of natural molecules (nucleosides) that play key roles in living cells.
According to the researchers, their synthesis method could be used in pharmacology, as these nucleoside analogs exhibit antiviral, anticancer, anti-inflammatory, and analgesic properties. The results were published in the European Journal of Organic Chemistry.
One of the study’s authors, Konstantin Savateev, an associate professor at the Scientific-Educational and Innovation Center of Chemical-Pharmaceutical Technologies at UrFU, explained that synthetic nucleoside analogs are crucial in pharmacology due to their close resemblance to naturally occurring compounds. This structural similarity allows the artificial molecules to “trick” viruses or cancer cells, integrating into their biological processes. This disrupts vital energy and informational functions in pathogens, leading to their degradation and death.
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